NFC Championship early look: 49ers-Rams betting odds and angles

The second game of the NFL Conference Championship Weekend will be an NFC West battle between the San Francisco 49ers and Los Angeles Rams.

This will be the third matchup this season between these two teams, with San Francisco winning both so far (and six straight against the Rams). Los Angeles will be the host, with action kicking off at 6:30 p.m. EST.

As we begin our prep for NFL Sunday, let’s acquaint ourselves with the betting odds for this game, trends to keep in mind, and overall betting thoughts and angles for this game.

For full coverage of the weekend, don’t miss our AFC Championship Game betting preview.

49ers vs. Rams: Odds and Betting Trends

Odds via DraftKings

  • Spread: Rams -3.5
  • Moneyline: 49ers +150 | Rams -170
  • Total: 46 points

San Francisco Betting Trends

San Francisco, at 12-7, has won four straight games, with three straight on the road. 

The 49ers are 11-8 against the spread this season, 7-4 ATS on the road and 4-1 ATS as an underdog.

Overs are just 8-11 in San Francisco games this season, a record that goes down to 1-4 when the Niners are an underdog. On the road, overs are 4-7 in 49ers games.

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Los Angeles Betting Trends

The Rams (14-5) have won seven of their past eight games, with the lone loss a late-game collapse against this very same San Francisco team in Week 18.

Los Angeles is 10-9 ATS this season, 5-4 ATS at home but just 7-9 ATS as a favorite.

Overs are 10-8-1 in Rams games this season, the fifth-best mark in the league. At home, that record dips to 4-5, and overs are 7-8-1 in games Los Angeles is favored.

Approaching the Game: Against the Spread and Over/Under

This game has so many intriguing levels to it. Kyle Shanahan and the 49ers have absolutely owned the Rams and Sean McVay the past three years with a perfect 6-0 mark.

You see that, and one has to wonder if it will just be more of the same this Sunday.

The first meeting this year wasn’t close, with San Francisco winning at home, 31-10. It took overtime in Week 18 for the 49ers to win again in what was a must-win scenario for the 49ers to clinch a postseason berth.

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